Harpoon 5-Miler – Boston, MA 2026

Join us for the 25th Annual Harpoon 5-Miler on Saturday, May 16, 2026! Registration is now CLOSED. The Harpoon 5-Miler in South Boston is not just a race—it’s a celebration of community, fitness, and hope. This annual event brings together runners, volunteers, and supporters from all walks of life to raise critical funds for two important charities: The Angel Fund for ALS Research and the Peter Frates Family Foundation . Over the years, the race has raised over $3.1 million for the cure and care of ALS, making a real impact in the fight against this devastating disease. Participants will race through the vibrant streets of South Boston ‍♂️ ‍♀️, all while supporting groundbreaking ALS research and honoring the legacy of Peter Frates, whose battle with ALS inspired the global Ice Bucket Challenge . With a beautiful course, a lively atmosphere, and the support of the Harpoon Brewery , the race is a must-do for anyone looking to challenge themselves, give back, and make a differe